Menu
 

BestReviews is reader-supported and may earn an affiliate commission. Details

Pets Cleaning Supplies

Best Pet Urine Eliminators

Updated May 2025
Bottom line
Pros
Cons
Best of the Best
Rocco & Roxie Professional Strength Pet Stain and Odor Eliminator
Rocco & Roxie
Professional Strength Pet Stain and Odor Eliminator
Best for Cats

A tried and trusted pet urine and stain eliminator with a wide range of uses. This product is especially well-loved by cat owners who struggle with stubborn urine odors.

Check Price
Check Price at Amazon
Best for Cats
Bottom Line

A tried and trusted pet urine and stain eliminator with a wide range of uses. This product is especially well-loved by cat owners who struggle with stubborn urine odors.

Pros

Enzymatic formula feeds on organic matter to thoroughly remove stains and odors. Discourages remarking. Safe to use on all surfaces and can be sprayed directly onto cat litter to eliminate odors. Free of chlorine and hazardous propellants. Stamped with the Carpet and Rug Institute's Seal of Approval.

Cons

Pricey considering the volume. Heavily soiled surfaces may require multiple applications.

Resolve Urine Destroyer Spray
Resolve
Urine Destroyer Spray
Trusted Brand

This strong spray works fast and digs deep to eliminate as much odor as it can.

Check Price
Check Price at Amazon
Trusted Brand
Bottom Line

This strong spray works fast and digs deep to eliminate as much odor as it can.

Pros

It works immediately on contact to take away the brunt of the urine and its smell, plus other pet stains. It's safe for most surfaces, including most fabrics and even hard surfaces like wood or tile.

Cons

There's a slight chemical smell, but it's still safe for use around people and animals.

Simple Solution Extreme Pet Stain and Odor Remover
Simple Solution
Extreme Pet Stain and Odor Remover
Easy Application

An enzymatic cleaner that attacks and destroys bacteria to clean from the ground up.

Check Price
Check Price at Amazon
Easy Application
Bottom Line

An enzymatic cleaner that attacks and destroys bacteria to clean from the ground up.

Pros

Offers pro-grade strength. Nozzle delivers three types of spray: stream, foam, and mist, so you can customize your cleaning experience. Comes from a trusted brand.

Cons

May not work quite as well on old stains as it does for odors.

Nature's Miracle No More Marking Stain and Odor Remover
Nature's Miracle
No More Marking Stain and Odor Remover
Heavy-Duty

Whether your pet has a penchant for peeing on couches, carpets, hard floors, or beds, this scented product is gentle on surfaces and tough on odors. Highly effective at removing odors and stains.

Check Price
Check Price at Walmart
Heavy-Duty
Bottom Line

Whether your pet has a penchant for peeing on couches, carpets, hard floors, or beds, this scented product is gentle on surfaces and tough on odors. Highly effective at removing odors and stains.

Pros

Enzymatic cleaning action breaks down bacteria to completely remove urine odors rather than simply masking them. Eliminates stains, too. Discourages dogs from returning to problem areas. Lemongrass and cinnamon fragrance.

Cons

Not suitable for hardwood, leather, and suede materials.

TriNova Natural Pet Stain and Odor Eliminator
TriNova
Natural Pet Stain and Odor Eliminator
Eco-friendly & Gentle

A solid choice if you're looking for an all-natural pet urine eliminator that works. Ideal for animals, children, and pet parents who are sensitive to chemicals and harsh fragrances.

Check Price
Check Price at Amazon
Eco-friendly & Gentle
Bottom Line

A solid choice if you're looking for an all-natural pet urine eliminator that works. Ideal for animals, children, and pet parents who are sensitive to chemicals and harsh fragrances.

Pros

Natural organic ingredients are safe for the whole family. Natural enzymes feed off biological waste to remove odors and stains in a single step. Ideal for use on hard-to-clean fabrics like carpets, rugs, mattresses, and upholstery. Leaves a mild herbal fragrance. Easy-use spray bottle comes in handy for spot cleaning.

Cons

Old, dried accidents might require an extra application or two.

Why trust BestReviews?
BestReviews spends thousands of hours researching, analyzing, and testing products to recommend the best picks for most consumers. We only make money if you purchase a product through our links, and all opinions about the products are our own. About BestReviews  
BestReviews spends thousands of hours researching, analyzing, and testing products to recommend the best picks for most consumers. We only make money if you purchase a product through our links, and all opinions about the products are our own. About BestReviews  
BestReviews spends thousands of hours researching, analyzing, and testing products to recommend the best picks for most consumers. We buy all products with our own funds, and we never accept free products from manufacturers.About BestReviews 
How We Tested

We recommend these products based on an intensive research process that's designed to cut through the noise and find the top products in this space. Guided by experts, we spend hours looking into the factors that matter, to bring you these selections.

Click here for testing insights
First Reviewed
October 30, 2021
36
Models
considered
8
Hours
researched
Category cover

Shop Similar Products Get the best products related to our top picks

ChomChom Roller Reusable Lint Roller
ChomChom Roller
Reusable Lint Roller
Check Price
4Knines Dog Seat Cover
4Knines
Dog Seat Cover
Check Price
TriNova Natural Pet Stain and Odor Eliminator
TriNova
Natural Pet Stain and Odor Eliminator
Check Price
Scotch-Brite 50% Stickier Lint Roller (6 pack)
Scotch-Brite
50% Stickier Lint Roller (6 pack)
Check Price
Urpower Dog Car Seat Cover
Urpower
Dog Car Seat Cover
Check Price
Melinda Harris
Written by Melinda Harris

Updated May 2025

Ready to buy now? Shop the best: 

If you're a pet parent, chances are you've dealt with your fair share of accidents. Whether you’re potty training a new puppy, dealing with a territorial kitty, or have an older companion who can’t always make it to the toilet on time, a pet urine eliminator can help keep your house smelling like home. Aside from lingering, tear-inducing odors, pet urine can also leave stubborn stains on carpets, rugs, and upholstery. Depending on your furbaby’s preferred problem area, you might want to consider a pet urine eliminator that also takes care of stains. While some pet urine eliminators simply have a deodorizing effect, others remove both stains and odors. Enzymatic formulations excel at eliminating both stains and smells by feeding off odor-causing bacteria before drying up and disintegrating. However, not all pet urine eliminators are suitable for every surface, so remember to check the usage indications before buying. (See our review on enzymatic cleaners for more information.)

Our Top Picks
Rocco & Roxie
Best of the Best
Rocco & Roxie
Professional Strength Pet Stain and Odor Eliminator
Bottom Line
A tried and trusted pet urine and stain eliminator with a wide range of uses. This product is especially well-loved by cat owners who struggle with stubborn urine odors.
Shop Now
Resolve
Best Bang for the Buck
Resolve
Urine Destroyer Spray
Bottom Line
This strong spray works fast and digs deep to eliminate as much odor as it can.
Shop Now
Simple Solution
Top Pick
Simple Solution
Extreme Pet Stain and Odor Remover
Bottom Line
An enzymatic cleaner that attacks and destroys bacteria to clean from the ground up.
Shop Now
Nature's Miracle
Top Pick
Nature's Miracle
No More Marking Stain and Odor Remover
Bottom Line
Whether your pet has a penchant for peeing on couches, carpets, hard floors, or beds, this scented product is gentle on surfaces and tough on odors. Highly effective at removing odors and stains.
Shop Now
TriNova
Top Pick
TriNova
Natural Pet Stain and Odor Eliminator
Bottom Line
A solid choice if you're looking for an all-natural pet urine eliminator that works. Ideal for animals, children, and pet parents who are sensitive to chemicals and harsh fragrances.
Shop Now
Related Reviews
Show More
Related Articles
Show More
You Might Also Like
Show More