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Best Antifungal Creams

Updated April 2023
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Best of the Best
Lotrimin AF Ringworm Cream
AF Ringworm Cream
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Trusted Brand
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It works, thanks to the 1 percent Clotrimazole formula, making it our medical expert's first recommendation.


Formulated specifically to treat ringworm, but also effective for other fungal infections. Garners praise for how well it controls itch and reduces redness.


Product may separate after being stored for long periods, especially in warm locations.

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Globe Clotrimazole Antifungal Cream
Clotrimazole Antifungal Cream
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According to our medical expert, this antifungal cream contains tolnaftate, which studies have proven is an effective treatment of ringworm.


It's an over-the-counter topical cream effective for treating ringworm and jock itch. The active ingredient is Clotrimazole, which is proven to relieve itching, burning, and cracking of the skin.


It takes slightly longer to kick in than other antifungal creams.

Triple Paste AF Antifungal Nitrate Medicated Ointment, 2 oz.
Triple Paste AF
Antifungal Nitrate Medicated Ointment, 2 oz.
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Most Versatile
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This antifungal cream's waterproof properties make it great for more active people, according to our medical expert.


Stands out for its waterproof formula that contains 2 percent Miconazole to treat fungus and zinc oxide to soothe skin. Works on a variety of fungal conditions and soothes skin.


Has a thick consistency that isn't as easy to spread as others. Contains corn starch.

Globe 2 percent Antifungal Cream, 1 oz.
2 percent Antifungal Cream, 1 oz.
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Best for Minor Treatments
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Don't discount this product if you have mild to moderate issues to treat, but you may want to consider another brand for major problems.


Made with 2 percent Miconazole Nitrate in a formula that controls itching and discomfort while treating a variety of fungal skin issues, such as jock itch and athletes' foot.


Its effectiveness in tough-to-treat fungal infections is questionable. Scent is unpleasant.

Family Care Clotrimazole Antifungal Cream, 1 oz. each, Pack of 5
Family Care
Clotrimazole Antifungal Cream, 1 oz. each, Pack of 5
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Basic Yet Effective
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Though the brand isn't as popular as competitors, the formula is very similar – plus you get a lot for the price.


With 1% Clotrimazole – one of the most effective anti-fungal medications – it tackles problem areas and soothes itching. Five tubes for one price also makes this pick an awesome deal.


Mixed reviews for how well it works on tough fungal infections such as ringworm.

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BestReviews spends thousands of hours researching, analyzing, and testing products to recommend the best picks for most consumers. We only make money if you purchase a product through our links, and all opinions about the products are our own. About BestReviews  
BestReviews spends thousands of hours researching, analyzing, and testing products to recommend the best picks for most consumers. We buy all products with our own funds, and we never accept free products from manufacturers.About BestReviews 

We recommend these products based on an intensive research process that's designed to cut through the noise and find the top products in this space. Guided by experts, we spend hours looking into the factors that matter, to bring you these selections.

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Buying guide for Best antifungal creams

Antifungal creams help kill off fungal cells. They treat fungal infections that have affected the skin or nails and are not meant to be ingested or used internally. Fungal infections of the skin are much less severe than internal ones, which is why you can purchase antifungal creams over the counter.

You can get a fungal infection pretty much anywhere on your body, but it's very common for people to get fungal infections on their feet. A weak immune system is a risk factor that can make people more susceptible to contracting fungal infections. Topical treatment is the first line of therapy for fungal infections, but you can take oral antifungal medications if the infection is severe enough.

We've put together information on what to consider when selecting an antifungal cream in our shopping guide, where you’ll also find symptom information for the most common fungal infections and tips to help you cope.

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Fungus thrives in moisture. Avoid wearing wet socks, a damp swimsuit, or sweaty workout clothes longer than you need to.

Questions to ask when shopping for antifungal cream

What ailment are you seeking to treat?

Different types of fungus require different types of antifungal cream. The packaging or label may tell you whether a cream is useful for treating a particular ailment. If not, look for the active ingredient. For example, terbinafine is effective for treating ringworm, jock itch, and athlete's foot. Miconazole is used to treat the aforementioned ailments and yeast infections, too.

Some antifungal creams include ingredients that help with other symptoms as well, such as inflammation.

"Do you have an itch that won’t go away? It could be a dry skin condition like eczema, but don’t discount the possibility of a fungal infection. "

How potent do you need the medication to be?

The amount of actual medication in an antifungal cream is displayed on the packaging. A cream may not be potent enough to treat your infection if you have ignored it for a length of time. If your infection is not responding to topical treatments, please visit a doctor, as you may require a stronger prescription or an oral medication.

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Testing antifungal creams
We spent 68 hours researching 25 creams and consulting 128 consumers before choosing our top 5 picks.

Are you allergic to any medications?

If you're allergic to any kind of medication, ask your pharmacist whether it's safe to use an antifungal cream. If you're taking any other medications, it's also wise to inquire about possible interactions. And if you’re unsure of what kind of skin condition you have, see a doctor. Please also keep in mind that some antifungal creams used for vaginal fungal infections or the treatment of jock itch can damage contraceptive devices such as condoms.

How much medication do you need?

Treatment of a fungal infection can last from 2 weeks to 6 weeks depending on your skin condition. Choose an appropriately sized tube or container of cream so you don't run out and skip a treatment day. If your condition requires lengthy treatment, a larger tube would probably be less expensive in the long run.

Do you have sensitive skin or another skin condition?

People with sensitive skin should opt for an antifungal cream with moisturizer or an ingredient like aloe vera to prevent over-drying and irritation. Users with eczema should be careful when choosing a topical fungal treatment.

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Expert tip
 Use the cream or ointment only as instructed, and do not ingest
BestReviews Medical Expert

Would you prefer an odorless antifungal cream?

Most medicated creams have some kind of odor, but for people who are sensitive to strong smells, odorless creams are available.

For those with sensitive skin, perfumed cream can cause an allergic reaction. Many antifungal treatments designed to treat vaginal yeast infections have strong flowery scents. These can irritate some women and may also mask smells that signal a more severe infection or issue. Choose an unscented antifungal cream if you are prone to reactions or have sensitive skin.

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Expert tip
If the infection does not improve after two weeks or gets worse, consult a doctor as it may be another condition
BestReviews Medical Expert

Should you buy a waterproof antifungal cream?

A waterproof antifungal cream is a good idea for athletes or others who don't want to worry about sweat washing off their treatment. It’s also useful for forgetful users who might end up showering after applying the medicated cream.

Types of fungal infections

Various fungal infections can affect the skin. Mild cases can be treated with topical creams, gels, or ointments. More severe skin infections may require the use of oral antifungals.

Below, you'll find a list of fungal-related skin conditions and their symptoms. If you’ve never been diagnosed with a fungal infection, see your doctor to make sure the skin problem is not something else. The symptoms listed below are not exhaustive and should not be read as such.

"If ever in doubt, visit your doctor to get a proper diagnosis for your skin condition. "

Athlete's foot

Symptoms include painful cracking and irritation of the skin in the foot area and severe itching.

Jock itch

Symptoms include itching or the development of a rash in the groin and surrounding areas.


Ringworm causes a distinct, ring-shaped rash that can easily be spread via direct skin contact.

Yeast infection

Symptoms of a yeast infection include uncomfortable itching in the area of the vagina and abnormal discharge. Self-diagnosis is not recommended, as many other conditions have similar symptoms.

"Store your antifungal cream according to package instructions. Normally, a location that’s cool and dry is best."


Q. How much does antifungal cream cost?

A. You’re not likely to pay more than $30 for a topical antifungal treatment, although price will increase with the size of the container or tube. Generally speaking, price does not correlate with quality or effectiveness when it comes to antifungal creams.

Q. What kind of fungal infections can be treated using antifungal cream?

A. Antifungal creams can treat a variety of fungal infections including but not limited to ringworm, athlete's foot, and vaginal yeast infections.

Q. Are there any side effects to using antifungal creams?

A. One of the advantages of topical treatments is that they have very few known side effects. One of the worst symptoms that could occur is irritation or rash in some individuals.

Q. Are there ways to prevent picking up a fungus and getting fungal infections on my feet?

A. Although some people are certainly more susceptible to this type of infection, everyone can lower their risk of contracting a foot fungus. Cover your feet in public areas, especially those that are known for being moist or wet. Keep your feet dry; fungus likes moisture! If you are prone to sweaty feet, use powders or sweat-wicking socks to keep moisture at bay.

expert tip
Store antifungal cream at room temperature.
BestReviews Medical Expert

Q. How can I tell if I have a fungal infection on my nails?

A. If your nails have been infected by fungus, they'll usually look discolored (probably yellow in color) and will break or crumble easily. A foul smell is often associated with fungal infections.

Q. How can I prevent future yeast infections?

A. It's unfortunate that some women are prone to this uncomfortable type of infection. Some strategies for preventing future yeast infections include avoiding tight clothing, changing out of wet or damp clothes immediately after a swim or workout, and changing tampons or pads frequently. A healthy diet is essential in helping prevent yeast infections. It's also recommended that women avoiding the practice of douching, as this can harm the natural pH balance of the vagina.

Q. I spend lots of time at the public pool. How can I protect myself from fungal infections?

A. Whatever you do, avoid going barefoot anywhere. Fungal infections are very contagious, and it's easy to pick them up just by walking in the same place as someone else affected. Get some water shoes, or wear sandals or other protective footwear until you get into the water. When heading back home, make sure your body is completely dry before putting on your socks, shoes, and other clothing.