Best Cat Heartworm Medications

Updated September 2020
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BestReviews spends thousands of hours researching, analyzing, and testing products to recommend the best picks for most consumers. We only make money if you purchase a product through our links, and we never accept free products from manufacturers. Read more  
BestReviews spends thousands of hours researching, analyzing, and testing products to recommend the best picks for most consumers. We buy all products with our own funds, and we never accept free products from manufacturers.Read more 
Bottom Line
Pros
Cons
Best of the Best
Advantage Multi Topical Solution for Cats, 9.1-18 lbs, 6 treatments
Advantage Multi
Topical Solution for Cats, 9.1-18 lbs, 6 treatments
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Customer Favorite
Bottom Line

This broad-spectrum formula is most effective against flea infestations, but also addresses heartworm in cats and ferrets.

Pros

Addresses heartworms, fleas, and ticks with 1 treatment. Only requires 1 monthly application. Broad-spectrum approach. Also effective against ear mites. Minimal side effects reported.

Cons

Expensive price point. More effective on fleas than ticks. Results vary from cat to cat.

Best Bang for the Buck
Revolution Topical Solution for Puppy & Kitten, under 5 lbs, 3 treatments
Revolution
Topical Solution for Puppy & Kitten, under 5 lbs, 3 treatments
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Ideal For Kittens
Bottom Line

Some heartworm medications can be too strong for kittens, but this formula is ideal for younger cats and dogs.

Pros

Safe to use on both puppies and kittens. Can be used in combination with other flea, tick, or parasite treatments. Minimal side effects reported. Monthly treatment regimen. Topical formula is easy to apply.

Cons

Fleas can return after several weeks, especially in areas with high infestations.

Revolution Topical Solution for Cats, 5.1-15 lbs
Revolution
Topical Solution for Cats, 5.1-15 lbs
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Trusted Brand
Bottom Line

Revolution is a good choice when fast and effective results are vital, such as an active infestation with multiple cats.

Pros

Also effective against roundworm and hookworm. Addresses flea infestations and heartworm. Good secondary medication for flea control. Starts to work within hours.

Cons

Additional flea treatments may still be necessary. Not a fast-acting topical formula.

Interceptor Tablets for Dogs 51-100 lbs & Cats 12.1-25 lbs, 6 treatments
Interceptor
Tablets for Dogs 51-100 lbs & Cats 12.1-25 lbs, 6 treatments
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Easiest to Use
Bottom Line

This heartworm preventative targets parasites specifically, not fleas or ticks.

Pros

Chewable tablet easier to administer. Broad-spectrum treatment of parasites including tapeworm, heartworm and hookworm. Monthly treatment regimen. Less likely to trigger allergic reaction.

Cons

Soft packaging can damage pills during shipment.

Heartgard Chewable Tablets for Cats, 5-15 lbs, 6 treatments
Heartgard
Chewable Tablets for Cats, 5-15 lbs, 6 treatments
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Most Comprehensive
Bottom Line

This powerful formula kills heartworms and hookworms before they reach the dangerous adult stage.

Pros

Destroys heartworms at immature tissue stage. Also effective against hookworms at all life cycles. Chewable pills easier to administer. Medication is beef-flavored, appealing to cats.

Cons

Can be challenging to administer to cats that are hard to pill by nature.

Why trust BestReviews?
BestReviews spends thousands of hours researching, analyzing, and testing products to recommend the best picks for most consumers. We only make money if you purchase a product through our links, and we never accept free products from manufacturers. Read more  
BestReviews spends thousands of hours researching, analyzing, and testing products to recommend the best picks for most consumers. We only make money if you purchase a product through our links, and we never accept free products from manufacturers. Read more  
BestReviews spends thousands of hours researching, analyzing, and testing products to recommend the best picks for most consumers. We buy all products with our own funds, and we never accept free products from manufacturers.Read more 
How we decided

We purchase every product we review with our own funds — we never accept anything from product manufacturers.

12 Models Considered
5 Hours Researched
1 Experts Interviewed
223 Consumers Consulted
Zero products received from manufacturers.

We purchase every product we review with our own funds — we never accept anything from product manufacturers.

Heartworm is a very dangerous medical condition caused by parasitic worms that enter the cat's bloodstream through infected foods, fleas, or ticks. The best treatment for heartworm is prevention, and this is what prescription-grade heartworm treatments provide. Heartworm medications are often combined with flea and tick medications for a more comprehensive treatment plan, but they can also be sold as a separate product. It is important that cat owners remain vigilant when administering heartworm medication, and to look for any signs of a possible heartworm infestation in the cat's feces. An actual case of heartworm often requires more aggressive treatment from a veterinarian.

Other Products We Considered
The BestReviews editorial team researches hundreds of products based on consumer reviews, brand quality, and value. We then choose a shorter list for in-depth research and testing before finalizing our top picks. These are the products we considered that ultimately didn't make our top 5.
Bayer
Tapeworm Dewormer for Cats, 3 tablets
Bayer Animal Health
Advantage II Flea Prevention, For Cats Over 9 lbs
Frontline Plus
Flea and Tick Treatment for Cats
FurroLandia
8-in-1 Dewormer for Dogs and Cats
Provecta
Advanced for Cats Over 9 Pounds, 4 doses
The team that worked on this review
  • Melinda
    Melinda
    Web Producer
  • Michael
    Michael
    Writer
×

Revolution

Topical Solution for Cats, 5.1-15 lbs

Revolution

Topical Solution for Cats, 5.1-15 lbs

Revolution is a good choice when fast and effective results are vital, such as an active infestation with multiple cats.
$0
×

Interceptor

Tablets for Dogs 51-100 lbs & Cats 12.1-25 lbs, 6 treatments

Interceptor

Tablets for Dogs 51-100 lbs & Cats 12.1-25 lbs, 6 treatments

This heartworm preventative targets parasites specifically, not fleas or ticks.
$0
×

Heartgard

Chewable Tablets for Cats, 5-15 lbs, 6 treatments

Heartgard

Chewable Tablets for Cats, 5-15 lbs, 6 treatments

This powerful formula kills heartworms and hookworms before they reach the dangerous adult stage.
$0
×

Advantage Multi

Topical Solution for Cats, 9.1-18 lbs, 6 treatments

Advantage Multi

Topical Solution for Cats, 9.1-18 lbs, 6 treatments

This broad-spectrum formula is most effective against flea infestations, but also addresses heartworm in cats and ferrets.
$0
×

Revolution

Topical Solution for Puppy & Kitten, under 5 lbs, 3 treatments

Revolution

Topical Solution for Puppy & Kitten, under 5 lbs, 3 treatments

Some heartworm medications can be too strong for kittens, but this formula is ideal for younger cats and dogs.
$0

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