5 Best Pet Insulin & Diabetes Medications - June 2026

A reliable alternative to Humulin that works similarly but is more affordable. A great option for pet owners who want an effective insulin as well as to save a bit of money treating their pets.

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PROS

Can be used in dogs and cats.
Cat owners rave about how well it works for their pets.
Ships fast and efficiently with cold-packing to keep it fresh.
Works well for most pets.

CONS

Just like with any insulin, hypoglycemia is possible if proper diet and veterinarian recommendations are not followed.
Rare reports of insulin vials not being completely full upon arrival.

BEST BANG FOR THE BUCK

Animal Necessity

DiaVetin Natural Diabetic Dog & Cat Supplement

Supplements Insulin

While it won't control insulin-dependent diabetes by itself, this supplement contains ingredients that may make keeping your pets blood sugar a bit easier and more effective.

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PROS

Formulated by vets with enzymes, vitamins, and nutrients to lower blood sugar naturally.
May result in diabetes control with lower insulin dosages in some pets with monitoring by a vet.
Can also be helpful for pets that don't quite need insulin.
Suitable for dogs and cats.
No prescription required.

CONS

Won't replace insulin in insulin-dependent pets.
Close monitoring of blood sugar levels and diet is a must.
Won't work for all pets.

Humulin

N Insulin

Trusted Brand

Humulin has a reputation for being effective at managing both feline and canine diabetes, but there are other, less expensive options available on today's market.

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PROS

Human insulin that's been a tried and trusted option for pets for decades.
Highly effective for most dogs and cats.
Trusted by vets and pet owners for the results it delivers.
Arrives well-packaged with cold packs, and ships quickly.

CONS

Can result in insulin resistance in pets with hard-to-control blood sugar levels.
Side effects common to insulin use such as lethargy and coma can occur if not monitored closely.
Priciest option.

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First Reviewed

November 08, 2021

Models
considered

Hours
researched

Written by Jennifer Manfrin

Updated August 2025

It’s frightening to get the diagnosis from your veterinarian that your pet has diabetes, but it usually doesn’t mean you can’t have many more years of enjoyment with your best friend. Just like diabetic humans rely on insulin, these life-saving medications are available for cats and dogs. The type of insulin and dosage that your diabetic pet will need will be determined by your vet, and can keep her from experiencing complications and further problems when given accordingly. In addition, medication in pill form is suitable for some cats that don't require insulin. There are also some natural supplements available for diabetic cats and dogs, but typically must be used in conjunction with prescribed insulin to keep blood sugar levels in check.

Best Pet Insulin & Diabetes Medications

Pros and Cons

Pros and Cons

Pros and Cons

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