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Best Pet Digestion & Enzyme Medications

Updated June 2023
Bottom line
Pros
Cons
Best of the Best
Nusentia Enzyme Miracle Digestive & Metabolic Dog & Cat Supplement
Nusentia
Enzyme Miracle Digestive & Metabolic Dog & Cat Supplement
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Multi-purpose Enzymes
Bottom Line

Whether you are looking for an enzymatic supplement for your pet's digestive problems or to improve other aspects of her overall health, this product's broad spectrum enzymes are highly effective.

Pros

In addition to improving digestive issues, this product's 8 enzymes can also reduce inflammation, decrease yeast development, and improve metabolism in some animals. Repeat users swear by its benefits for pets that are prone to diarrhea.

Cons

Some pets didn't like the flavor. Like most products in this category, it may not work for all dogs and cats, but it is very effective for most that try it.

Best Bang for the Buck
Animal Essentials Plant Enzyme & Probiotics Dog & Cat Supplement
Animal Essentials
Plant Enzyme & Probiotics Dog & Cat Supplement
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Best for Sensitive Pets
Bottom Line

A dual-action digestive support product that has earned a loyal customer following for the benefits it delivers. The combination of enzymes and probiotics works well for many dogs and cats that are prone to stomach issues.

Pros

Contains both enzymes and probiotics that boost digestion and calm sensitive stomachs. Enzymes are plant-based. May decrease episodes of vomiting in some pets. Only a small amount is needed for noticeable results in most pets.

Cons

Some dogs and cats don't like it. Tends to get clumpy once moist if not sprinkled evenly over food.

NaturVet Advanced Probiotics & Enzymes Cat & Dog Supplement
NaturVet
Advanced Probiotics & Enzymes Cat & Dog Supplement
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Tempting Flavor
Bottom Line

Worth considering for pet owners who need a digestive supplement with appealing flavor. If side effects occur, they are likely to ease up in most pets when taken on a regular basis.

Pros

Formulated especially for pets with sensitive stomachs. Contains enzymes that improve digestion and promote the growth of good bacteria in the digestive system. Easy to administer, as most dogs and cats love the flavor. Available in powder for dogs and cats and tasty chews for dogs.

Cons

May cause gas in some pets that is likely to improve with repeated use. Some owners report that their pets developed diarrhea after taking it.

Glandex Profivex Five Strain Probiotic with Fiber and Sweet Potato Dog & Cat Supplement
Glandex
Profivex Five Strain Probiotic with Fiber and Sweet Potato Dog & Cat Supplement
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Packed with Probiotics
Bottom Line

This digestive supplement is formulated to target digestive problems, and may be beneficial to dogs and cats with compromised digestive systems due to antibiotics.

Pros

Soothes tummy issues with 2 strains of prebiotics and 3 strains of probiotics that increase the development of "good" bacteria in the gut. Supports digestive systems of dogs and cats that are taking antibiotics. Some dog owners report improvement in anal gland issues.

Cons

Some pets, especially cats, refused to eat it. Can cause gas at first, but this symptom usually resolves with frequent use.

Herbsmith Microflora Plus for Digestion Capsules Daily Dog & Cat Supplement
Herbsmith
Microflora Plus for Digestion Capsules Daily Dog & Cat Supplement
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Best for Dogs
Bottom Line

If you are looking for a digestive support for your pet in capsule form, this one is worth considering. It's especially suited for dogs that take disguised pills easily.

Pros

Microflora Plus's combination of enzymes, probiotics, and prebiotics calms digestive issues and improves digestion. Capsule form is easy to give to dogs that will take medications hidden in treats. Consumers brag about improved stools when their pets take it regularly.

Cons

The downside of the capsule form is that it can be difficult to give to some cats.

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BestReviews spends thousands of hours researching, analyzing, and testing products to recommend the best picks for most consumers. We only make money if you purchase a product through our links, and all opinions about the products are our own. About BestReviews  
BestReviews spends thousands of hours researching, analyzing, and testing products to recommend the best picks for most consumers. We buy all products with our own funds, and we never accept free products from manufacturers.About BestReviews 
HOW WE TESTED

We recommend these products based on an intensive research process that's designed to cut through the noise and find the top products in this space. Guided by experts, we spend hours looking into the factors that matter, to bring you these selections.

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Many cats and dogs are prone to sensitive digestive systems and as a result, experience symptoms that can be uncomfortable to pets and their owners. Difficulties with digestion can lead to upset stomach, gas, diarrhea, and loss of appetite as well as worried, frustrated owners. That’s when digestive support and enzyme medications can help. These products are designed to ease digestive distress by promoting digestion and easing symptoms, thanks to enzymes, probiotics, and prebiotics that help break down food and improve absorption. In addition, they also promote the growth of “good” bacteria that can eliminate gas and make stools firmer when taken on a regular basis. Digestive support supplements may also inhibit the growth of yeast and reduce inflammation.