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Buying guide for best whole body detox cleanses

Between pollution, pesticides, medicinal chemicals, and unhealthy food additives, our bodies are forced to endure a never-ending onslaught of toxins. While the miraculous human system is already fully equipped to rid itself of impurities, a whole-body detox cleanse can help speed up the process and take some pressure off your hard-working organs. Whether you’re feeling bloated, sluggish, or simply want to kickstart a new diet with a clean slate, a whole-body detox cleanse can help you hit the reset button, enabling your system to fire on all cylinders.

However, with endless options on the market, choosing the right detox cleanse isn’t easy. Ingredients can vary dramatically from product to product, and to make things even more confusing, different detoxes often have different cleansing benefits.

If you need help finding the best formula for your detox goals, keep reading. Our in-depth guide is crammed with essential information and handy tips to get you off to a great start.

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Lingering toxins from frequent exposure to pollution, prescription drugs, and bad dietary choices can slow metabolism and hinder weight loss. Flushing impurities from your system can work wonders for your overall well-being, but the benefits aren’t limited to internal bodily functions. In fact, many people find that whole-body detox cleanses also leave their hair and skin looking and feeling revitalized.

Key considerations

Your detox goals

Many turn to whole-body detox cleanses primarily as a weight loss aid, but did you know they can also be helpful in assisting optimal organ function, restoring digestive balance, and boosting overall energy levels?

If you’re hoping to shed a few pounds, opting for a fiber-rich formula with natural diuretic and laxative properties can help reduce bloating, jump-start weight loss, and might even encourage healthier eating habits. On the other hand, cleanses that are rich in antioxidants, vitamins, minerals, and probiotics provide extra support for organs like the liver and kidneys and can help you feel more energized and rejuvenated by shouldering some of the strain of vital bodily functions.

For the best total-body cleansing results, we recommend choosing a supplement that offers complete digestive and organ detoxification support.


While ingredients can differ from product to product, there are a handful of detox staples that have earned a well-deserved place on many nutritional labels. Familiarizing yourself with the common ingredients used in whole-body detox cleanses can help you find the most effective formula for your needs.

  • Milk thistle: Revered for its liver-cleansing properties, milk thistle is a potent antioxidant. However, its detox benefits are far-reaching and can also help reduce general inflammation, boost digestive function, and promote healthier mucus membranes.

  • Dandelion root: A long-trusted natural remedy for everything from constipation to water retention, dandelion root (and greens) have been shown to pack a powerful diuretic and liver-detoxifying punch. Dandelion root also encourages increased bowel movements, which can further help minimize bloating.

  • Lactobacillus acidophilus: This multitasking probiotic is a great addition to any whole-body detox cleanse. Aside from promoting improved overall gut health, L. acidophilus also decreases the growth of harmful bacteria in the digestive tract, helps break down lactose (milk sugar), prevents urinary tract infections, combats diarrhea, boosts the immune system, and can even aid in weight loss.

  • Aloe vera: Just about everyone is familiar with aloe vera and its bevy of health benefits. A medicinal powerhouse, aloe vera is chock-full of vitamins, minerals, and antioxidants to keep your body nourished while eliminating toxins at the same time. Great for digestion, aloe vera supports regular bowel movements, keeping toxins moving out of your system. Alkaline in nature, aloe vera can be especially helpful for digestive issues like heartburn, acid reflux, and gas.

  • Psyllium husk: A soluble fiber, psyllium husk acts as a natural and gentle laxative, helping your body rid itself of waste. Because psyllium husk absorbs water and expands within the digestive tract, it can create a feeling of fullness – a definite bonus for anyone looking to shed a few pounds. Psyllium husk can also help regulate blood sugar, cholesterol, and blood pressure.

  • Flaxseed: With a combination of soluble and insoluble fiber, flaxseed is a fantastic digestive cleanser, but its benefits don’t stop there. Rich in omega-3 fatty acids, flaxseed actively fights inflammation throughout the body, supports heart function, and assists in maintaining healthy blood pressure and cholesterol levels.

  • Acai berries: A veritable toxin-wrangling super fruit, acai berries are loaded with antioxidants, helping your body fight off oxidative stress caused by pollution, chemicals, and poor dietary choices. With the ability to reduce gastrointestinal inflammation, acai berries aid digestion and also reduce the symptoms of common digestive problems like irritable bowel syndrome and acid reflux.

  • Hawthorn extract: Hawthorn berries have earned a special place in the hearts of natural health enthusiasts for their broad spectrum of cardiovascular benefits. Both the berries and leaves have been used for centuries to treat a range of heart and circulatory conditions, including high blood pressure, angina, hardening of the arteries, and irregular heartbeat. Packed with potent antioxidant flavonoids, hawthorn extract actively roots out free radicals, reducing inflammation and improving overall health and vitality.

Detox length

Whole-body detox programs vary in length, ranging from just a few days to up to a month and sometimes even longer.

Although many short-term detoxes (one to two weeks) tend to focus on clearing the digestive tract, the best formulas also contain antioxidants, probiotics, and essential vitamins and minerals for a more comprehensive cleansing effect. Many people turn to short-term cleanses as a quick fix for constipation, bloating, and a general feeling of sluggishness. Quick detox cleanses with a mild laxative effect can leave you feeling a little lighter and can help you drop a few pounds, albeit temporarily.

Longer whole-body detox cleanses (two weeks to one month) tend to be gentler on the digestive system and might be more effective when it comes to steadily ridding the body of an overload of toxins and other impurities while supporting overworked organs. Most feature a well-balanced blend of natural antioxidants, fiber, probiotics, and essential vitamins and minerals for a holistic effect that nourishes as it cleanses. If you’re considering a complete lifestyle change, feeling especially rundown, or need continued support for strained organs, an extended whole-body detox cleanse is worth considering.

Expert Tip


Complete detox guides

If you’re simply seeking a quick and easy total-body boost, following basic dosage instructions might be enough. However, if you’re interested in making long-term lifestyle changes, a comprehensive detox guide with easy-to-follow dietary advice and handy tips is sure to help you reach your desired goals. Some whole-body detox cleanses even include free e-books to guide you along every step of your cleansing journey.

Additional nutrients

A whole-body detox should help clear your system of impurities, but it most certainly shouldn’t deprive it of essential nutrients. Since many people use whole-body detox cleanses in conjunction with low-calorie diets to speed up weight loss, choosing a formula that’s enriched with nutrients like iron, calcium, zinc, vitamin B12, and omega-3 fatty acids is a good idea.

Pill size and dosage

Although not a major concern for everyone, pill size can be important, especially if your detox program requires you to take multiple doses per day. Smaller pills are easier to swallow and can make for a more pleasant experience overall. Certain detox kits even come with different pills for separate actions. Unless you don’t mind having to swallow a handful of pills each time you take a dose, consider choosing an option that includes all the necessary detoxification compounds in a single pill.


The price of a whole-body detox cleanse isn’t always the best indicator of how well it works. Often shorter cleanses cost less than their long-term counterparts, and those with fewer ingredients or limited action (such as simply encouraging regular bowel movements) will be cheaper than more comprehensive formulas. Checking the listed ingredients and usage instructions should give you a good idea of the type of results you can expect from any given detox cleanse.

Depending on the number of ingredients and their quality, short detox programs that last one to two weeks generally cost between $8 and $12.

Whole-body detox cleanses that last two weeks to a month can set you back anywhere from  $12 to $17.

Detox cleanses with lots of quality natural ingredients are generally priced between $17 and $30, depending on the dosage and whether or not they come with extras like detailed detox guides.


  • Always follow package instructions. While it can be tempting to take a double dose in the hopes of speeding up detox effects, exceeding daily dosage recommendations can cause unwanted side effects like diarrhea and dehydration.

  • Drink plenty of water. Often a considerable amount of water is flushed out of the system along with waste. Staying hydrated throughout your detox cleanse is essential to both your health and the product’s efficacy.

  • Try to eat a balanced diet. Even though many whole-body detox cleanses don’t require you to follow a special diet, eating a variety of fruits and vegetables along with lean protein will provide extra antioxidants, vitamins, fiber, and iron, which can help you stay healthy while optimizing detox benefits.

  • Avoid taking products with aggressive laxatives for extended periods of time. Even natural laxatives like senna and cascara sagrada can eventually interfere with normal digestive function when overused.

Other products we considered

If you didn’t find what you were looking for among our top five picks, the Renew Life Cleanse Smart Total Body Cleanse features a unique two-step program that is especially appealing if you’re concerned about needing to dash to the restroom during the day. This whole-body detox cleanse is jam-packed with quality ingredients and takes a two-pronged approach with a potent general detoxifying formula for mornings and a gentle but effective elimination blend for evenings. For those who prefer taking just one dose a day, the DDOT Full Body Cleanse is a fantastic alternative. With all the necessary components for a complete whole-body detox, plus added green tea and guarana extracts, this is a great option if you’re looking for a once-a-day supplement that will support weight loss as well.

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If you frequently forget to take daily supplements, a short-term whole-body detox cleanse might be your best bet.


Q. Are whole-body detox cleanses safe?

A. As long as you’re not pregnant or breastfeeding, allergic to any of the ingredients, drink plenty of water, keep your body well-nourished, and use the supplement as specified by the manufacturer, a whole-body detox cleanse should be perfectly safe. However, as with any new supplement, dietary adjustment, or exercise routine, it’s always best to consult with your physician before getting started.

Q. How often can I use a whole-body detox cleanse?

A. That depends on the combination and concentration of the ingredients. Certain short-term detox cleanses don’t pull any punches when it comes to clearing out the digestive tract and generally aren’t meant for regular use. To avoid becoming dependant on the laxative effects of these cleanses, it is best to limit use to no more than once a month or less. However, most long-term whole-body detox cleanses are gentler and can often be used as needed for extended periods of time. Before following up your initial detox with another round, check the manufacturer’s usage instructions to make sure it’s safe.

Q. Is it normal to have diarrhea on a whole-body detox cleanse?

A. Increased bowel movements, loose stools, and, in some cases, mild cramping can occur at the onset of a whole-body detox cleanse. However, if you experience severe cramping and diarrhea that doesn’t ease within a couple days, stop the cleanse immediately. You can then try a milder alternative once your body has had a chance to recuperate.

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