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Best Nootropics

Updated March 2023
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Pros
Cons
Best of the Best
Life Extension Cognitex Basics Brain Health Formula, 30 Count
Life Extension
Cognitex Basics Brain Health Formula, 30 Count
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Potent Formula
Bottom Line

Cognitex helps boost cognitive function, supports brain cell connections, improves memory, and is gluten free, which our nutrition expert notes will benefit those with celiac disease.. Life Extension's products are made in the USA.

Pros

Take one soft gel daily with or without food. Soft gels are easy to swallow. Users note improved memory and focus; some feel an improvement in mood and ability to concentrate. 1-year money-back guarantee on supplements.

Cons

Have to be consistent in taking soft gels every day for a while before feeling the effects.

Best Bang for the Buck
NeuroGum Gum Energy and Focus Nootropic
NeuroGum
Gum Energy and Focus Nootropic
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Quick Release
Bottom Line

A balanced-boost formula that delivers energy five times faster than coffee or energy drinks, and the gum is perfect for those who struggle to swallow pills.

Pros

Well-balanced nootropics formula. Infused with B-vitamins, L-theanine, and natural caffeine. Vegan formula. Free of aspartame, sugar, GMO, and gluten. Doesn't give jitters or a sugar crash. Pleasant minty flavor is invigorating. Ideal for those who don't like taking pills or powder supplements.

Cons

Some consumers feel the flavor is a bit too strong. Gum is a bit stickier than expected.

Huntington Labs Neuro Health Brain and Focus Formula, 60 Count
Huntington Labs
Neuro Health Brain and Focus Formula, 60 Count
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Best for Everyday Use
Bottom Line

Made in the USA and 100 percent natural, this supplement uses the properties of green tea to improve memory and focus for less than other brands.

Pros

Users like both the increase in overall memory and energy and report feeling more rested when waking in the morning. No caffeine as an ingredient, so no jitters as a side effect. Students are happy with improved focus during classes, studying, and test-taking.

Cons

Should take close to meals to prevent stomach upset; stay hydrated throughout the day, or supplement may cause headaches.

Double Wood Supplements Alpha GPC Choline Supplement, 60 Count
Double Wood Supplements
Alpha GPC Choline Supplement, 60 Count
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Simple Yet Solid
Bottom Line

Incorporating high manufacturing standards, quality ingredients, and a money-back guarantee, these daily-use capsules boast improved memory, mood, and motivation.

Pros

Alpha GPC crosses the blood-brain barrier as a highly absorbable kind of choline. Users report feeling more alert and able to concentrate. Unlike other ADHD medications, this supplement allows for more restful sleep as well as more focused waking hours.

Cons

Those with allergies are out of luck - this kind of choline is derived from soy. Some users complain of stomach upset.

Arazo Nutrition Brain Plus Nootropic Supplement, 60 Count
Arazo Nutrition
Brain Plus Nootropic Supplement, 60 Count
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Natural Option
Bottom Line

Not only does it improve brain function, this nootropic contains many other vitamins and minerals, though it may take time to see results, so our nutrition expert recommends consulting your doctor before taking.

Pros

Contains natural green tea extract and no caffeine. Great for keeping energy up while working long shifts. ADHD sufferers have taken this with better results than from their prescription medication. Users report better moods and memory; some feel their vision and social skills have improved.

Cons

May not work immediately; the manufacturer recommends taking for at least 2 months to determine efficacy.

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BestReviews spends thousands of hours researching, analyzing, and testing products to recommend the best picks for most consumers. We only make money if you purchase a product through our links, and all opinions about the products are our own. About BestReviews  
BestReviews spends thousands of hours researching, analyzing, and testing products to recommend the best picks for most consumers. We buy all products with our own funds, and we never accept free products from manufacturers.About BestReviews 
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Buying guide for Best nootropics

Nootropics are chemical and natural compounds that provide cognitive enhancement for brain functionality, such as increased concentration, memory, and focus. While it’s possible to find nootropic compounds in some specific foods, many people opt to take nootropic supplements.

Nootropics are also called “smart drugs,” and some are only available by prescription. Nootropic supplements, however, can be purchased without a prescription, and those are what we’ll focus on in this guide. When taken in the recommended amount, they are considered safe, non-addictive, and non-toxic. Of course, before beginning any new supplement, consult with your healthcare practitioner.

What are nootropics?

Nootropics are natural and synthetic substances used to improve mental performance. They boast cognitive enhancements such as improved memory, creativity, focus, intelligence, and motivation, claim to protect the brain from damage and degeneration, and offer other potential benefits.

Expert tip
Nootropics should be used with extreme caution. I recommend talking to your doctor before taking them.
BestReviews Nutrition Expert
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A potential benefit of nootropics is the coupling of the brain’s two hemispheres, allowing them to work together for better processing of information.

Synthetic vs. natural nootropics

While nootropics are legal, most should be used with caution. Synthetic nootropics are chemical compounds that often require a prescription. They can act as strong stimulants that may be habit forming and have serious side effects. These include but are not limited to:

  • Modafinil (Provigil)

  • Nuvigil

  • Adderall

  • Ritalin

  • Noopept (can be purchased as a supplement)

  • Pircetem

  • Phenotropil

  • Adrifinal
     

Some of these prescription drugs are used to treat serious conditions such as narcolepsy, brain injury, and epilepsy but when used as nootropics they have effects on memory and attention.

Natural nootropics have more subtle and slower-acting effects. However, they are considered safer to take and generally are not habit forming (with the exception of caffeine and nicotine). In some formulas, they are “stacked,” or taken in combination, to enhance their effects.

Following is a list of common ingredients found in natural nootropic blends. Taken alone, many of these compounds are also considered nootropics.

  • Caffeine is a naturally occurring chemical that increases alertness and attention and reduces reaction time and fatigue. It’s widely consumed worldwide in coffee, tea, chocolate, guarana, and sodas.

  • Medicinal mushrooms such as lion's mane, reishi, cordyceps, and chaga all have been shown in studies to support cognitive function. For example, lion’s mane is embraced for thwarting age-related mental decline as well as improving overall mental function and memory. Other mushrooms may help with increasing resilience in times of stress, fighting fatigue, boosting immunity, and protecting the brain.

  • Omega-3 fatty acids, a common health supplement, are also considered nootropics.  Essential building blocks for the brain, EPA and DHA are the two main types of omega-3 for brain health and can be found in certain fish and nuts and obtained from fish oil capsules. Omega-3 fatty acids can be classified as nootropics because they may support memory and focus, protect brain cells against damage, and also lower levels of depression.

  • L-theanine is a non-dietary amino acid found commonly in green and black tea. It has a calming effect without drowsiness. It is shown to reduce anxiety symptoms and improve concentration and alertness. It increases alpha waves in the brain, which may help with creativity. It is more effective when paired with caffeine, so performance supplements often contain them in tandem.

  • Bacopa monnieri is an herb used in Ayurvedic medicine to enhance brain function. Studies show it can speed up information processing, improve memory, and may even help treat ADHD and depression symptoms.

  • Creatine doesn’t just benefit bodybuilders looking to bulk up on muscle. As a nootropic, this amino acid binds with phosphate in your brain and creates an energy molecule that fuels your brain cells. This leads to increased memory and reasoning skills and also has benefits for reducing stress.

  • Rhodiola rosea along with other adaptogenic herbs are considered nootropics that help your body handle stress. If you experience stress-related fatigue, this adaptogen may boost your mental performance and concentration. It can also decrease feeling burned out, especially during stressful periods.

  • Panax ginseng is another adaptogen that can help manage stress. It induces feelings of calm and reduces brain fatigue associated with stress.

  • Ginkgo biloba supplements are extracted from ginkgo biloba leaves and are said to improve memory and mental processing in older adults. It also works to decrease levels of cortisol, the stress hormone. It has been widely studied for its potential anti-inflammatory and circulation-boosting effects on the brain.
     

This is just a partial list of popular, natural nootropics. There are plenty of other nootropic compounds available on the market. Many common vitamins and minerals are also considered nootropics.

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Expert tip
Some nootropics like caffeine and omega-3 fatty acids are more popular to take. 
BestReviews Nutrition Expert

Features

Dosage and product form

The recommended serving size or dosage of a nootropic will vary depending on the supplement and manufacturer. Most come in capsule form and require a dose of one to three capsules per day. Some capsules take several months to work.

Nootropics are also commonly available in powdered form. Powders can get messy, but they are absorbed by the body quickly and work well for those who want to avoid taking pills or capsules. One scoop into a glass of water or a favorite beverage is usually all you need as a daily dose.

Additional health support

Many companies have developed nootropic formulas that not only improve brain function but also provide health benefits in areas such as weight loss and athletic performance.

For example, supplementing a compound such as caffeine with L-theanine creates a popular nootropic stack that can increase energy and focus, while keeping the mind relaxed. This can be an effective mixture in improving focus and performance at the gym or limiting anxiety and distraction while dieting.

Keep in mind stacked formulas can potentially have side effects, depending on what other active ingredients a proprietary blend contains. Pay close attention to ingredients and labeling so you are certain you’re not getting anything you’re allergic to or can’t tolerate (like high levels of caffeine).

Expert tip
Use caution while taking generic nootropic supplements, as you might not know exactly what is in them. 
BestReviews Nutrition Expert

Nootropics prices

Inexpensive

The most affordable nootropics are generally pill formulas that land between $14 and $20. This is a great place to start for users new to nootropics. However, be aware that cheaper nootropic products may contain fillers and other unwanted ingredients.

Mid-range

Nootropics in the mid-level price range run from $21 to $39. This price range includes usually herbal and mushroom ingredients stacked for more potent results.

Expensive

The most expensive nootropic blends range from $40 to upwards of $100. Pricier blends tend not to include caffeine to boost the brain but an optimal combination of vitamins and herbs.

Tips

  • To reduce the risk of dependency or building up a tolerance, considering “cycling” nootropics. Take them for five to seven days, then take two days off.

  • If you’re prone to stress, try a nootropic with adaptogens, which boost your body’s resistance to stress and damage from high cortisol levels and increase mental focus. Look for ingredients containing Panax ginseng, ashwagandha, licorice root, rhodiola rosea, cordyceps, holy basil, and astragalus root.

  • If you’re looking to improve your memory, attention span, and processing speed, the best natural nootropic compounds to take are ginkgo biloba, caffeine in conjunction with L-theanine, or just caffeine.

  • If you’re looking to help clear brain fog and/or stabilize mood, nootropics containing medicinal mushrooms and adaptogenic herbs can help.

Content Image
Memory games are a great way to naturally boost your brain’s recollection power. About 30 minutes a day is all you need to see results in a short period of time.

FAQ

Q. Are nootropics safe for long-term use?

A. Because more research needs to be done for long-term use of synthetic and natural nootropics, we suggest exercising caution for long-term use.

Q. Are there significant side effects when taking nootropics?

A. Generally, no, when taking natural nootropics (supplements). Prescription synthetic nootropics do carry a whole host of side effects. Some users are more tolerant of certain supplements than others, so begin with lower dosages if you have concerns and work your way up to the recommended amount. Because formulas contain multiple components, and if you’re already taking a multivitamin or other supplements, be sure to check that you’re not doubling up on one component. Also some nootropics, like adaptogens, can interfere with prescription medications so be sure to check with your healthcare practitioner or physician before taking any supplement.

Q. What is the typical shelf life of nootropic formulas?

A. Like other supplements, nootropic products have expiration dates. You can extend your supplement’s shelf life by keeping it in a cool, dry environment like a medicine cabinet.