5 Best Pet Urinary Tract & Kidney Medicines- Sept. 2026

Baytril (Enrofloxacin) Tablets for Dogs & Cats

A highly-effective antibiotic that works well for treating urinary tract infections when taken as prescribed. Be sure your pet drinks plenty of water when taking this medication.

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PROS

An effective antibiotic that is commonly prescribed to treat urinary tract infections.
Used for dogs and cats.
Many pets experience quick relief once they begin taking this medication.

CONS

Side effects such as stomach upset, lethargy, and elevated liver enzymes are possible.
Dairy foods must be withheld for 2 hours after dosing for best results.

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Beloved Pets

Cat & Dog Urinary Tract Infection Medicine

For Urinary Tract Health

This wide-ranging medicine helps with kidney stones, UTIs, general irritation, and bladder support.

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PROS

It’s cranberry flavored and a liquid, making it easy to hide in food or mixed with broth and water.
There are detailed dosage instructions and it contains no chemicals, preservatives or fillers.

CONS

Some had issues with the included dropper not pulling in enough medicine.

Proin

Chewable Tablets for Dogs

For Canine Incontinence

Ask your veterinarian about Proin if your best friend tends to leak urine, as it is a medication that is quite effective at controlling this troublesome renal system concern.

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PROS

Earns praise from dog owners for how well it controls continence.
Effective for most dogs, and is frequently prescribed to senior canines that are prone to urinary leaking issues.
Prevents leaks by tightening muscles in the urethra and bladder.

CONS

Not for cats.
Although chewable, some dogs don't like the flavor, so owners still may have to conceal the tablets in treats or food.

Merck

Incurin Tablets

For Post-op Issues

These tablets target issues related to dogs that have been spayed, reducing or eliminating post-surgery urinary incontinence.

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PROS

Dosage is only once daily and the amount does not change based on age or weight.
Full treatment lasts for a minimum of 2 weeks.
The tablets are easy to hide in a treat or be crushed and mixed with food or water and broth.

CONS

It’s for dog use only and requires a prescription, so you need your vet's authorization.

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First Reviewed

November 09, 2021

Models
considered

Hours
researched

Written by Jennifer Manfrin

Updated August 2025

Just like their human owners, pets can also suffer from a variety of problems associated with the urinary tract and kidneys. Infections, incontinence, and kidney stones are the most common ailments, but some pets are also prone to more serious conditions of the renal system, including blockage, renal failure, and diseases that result in the need for a diuretic. The good news is that there are many medications that effectively treat pet urinary tract and kidney health conditions. If your pet is experiencing concerning symptoms, have him evaluated by your veterinarian. If the diagnosis is related to the renal system, prescription medications or supplements may be recommended that you can purchase hassle-free online.

Best Pet Urinary Tract & Kidney Medicine

Pros and Cons

Pros and Cons

Pros and Cons

Pros and Cons

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