Best Pet Urinary Tract & Kidney Medicine

Updated October 2020
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BestReviews spends thousands of hours researching, analyzing, and testing products to recommend the best picks for most consumers. We only make money if you purchase a product through our links, and all opinions about the products are our own. Read more  
BestReviews spends thousands of hours researching, analyzing, and testing products to recommend the best picks for most consumers. We buy all products with our own funds, and we never accept free products from manufacturers.Read more 
Bottom Line
Pros
Cons
Best of the Best
Baytril (Enrofloxacin) Tablets for Dogs & Cats
Baytril (Enrofloxacin)
Tablets for Dogs & Cats
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Best for Infections
Bottom Line

A highly-effective antibiotic that works well for treating urinary tract infections when taken as prescribed. Be sure your pet drinks plenty of water when taking this medication, and takes all prescribed doses.

Pros

An effective antibiotic that is commonly prescribed to treat urinary tract infections. Used for dogs and cats. Many pets experience quick relief once they begin taking this medication.

Cons

Side effects such as stomach upset, lethargy, and elevated liver enzymes are possible; but most pets tolerate it well. Dairy foods must be withheld for 2 hours after dosing for best results.

Best Bang for the Buck
NOW Pets Urinary Support Dog & Cat Supplement, 90 count
NOW Pets
Urinary Support Dog & Cat Supplement, 90 count
Check Price
For Urinary Tract Health
Bottom Line

If you are looking for a supplement that will promote urinary tract health and possibly prevent future issues, talk to your vet about this option.

Pros

Promotes a healthy pH level, which helps keep kidneys detoxified. May help prevent the development of urinary crystals, which can lead to blockage in some pets. Often recommended by vets to support urinary health. Can be taken by dogs and cats. Side effects aren't likely.

Cons

Although a prescription is not required, consultation with a vet is advised before use. Should not be taken long-term – talk to your for vet about the best regimen for your pet.

Proin Chewable Tablets for Dogs
Proin
Chewable Tablets for Dogs
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For Canine Incontinence
Bottom Line

Ask your veterinarian about Proin if your best friend tends to leak urine, as it is a medication that is quite effective at controlling this troublesome renal system concern.

Pros

Earns praise from dog owners for how well it controls continence. Effective for most dogs, and is frequently prescribed to senior canines that are prone to urinary leaking issues. Prevents leaks by tightening muscles in the urethra and bladder.

Cons

Not for cats. Although chewable, some dogs don't like the flavor, so owners still may have to conceal the tablets in treats or food.

Salix (Furosemide) Tablets for Dogs and Cats
Salix (Furosemide)
Tablets for Dogs and Cats
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Effectuve Diuretic
Bottom Line

In spite of possible side effects, this medication outweighs the risks when prescribed for pets with serious ailments such as renal or heart failure. However, it's important to inform your vet if serious side effects occur.

Pros

This diuretic is a trusted medication that is frequently prescribed to promote the removal of fluid due to a variety of health conditions, including kidney failure. Can be prescribed for dogs and cats. Pills are scored and easy to split.

Cons

Possibility of side effects, some potentially serious, such as dehydration, electrolyte imbalance, vomiting, and depressed mood. Some pets may spit them out if not concealed well in food.

Normosol-R Electrolyte Injection Solution
Normosol-R
Electrolyte Injection Solution
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Replaces Fluids
Bottom Line

Although administering fluids isn't easy for all pet owners to do, it's an option that can prolong the life of dogs and cats with severe kidney damage or renal failure.

Pros

Prescribed as a fluid replacement therapy for pets with severe kidney malfunction or failure. Side effects aren't likely when given exactly as prescribed. Can make very sick pets function normally when given as directed by a veterinarian.

Cons

Must be administered subcutaneously, which can be difficult for some consumers. Allergic reactions are rare, but possible. Infection at the site of injection can occur. Giving too much at one time can cause hyperkalemia (high potassium).

How we decided

We purchase every product we review with our own funds — we never accept anything from product manufacturers.

56 Models Considered
16 Hours Researched
2 Experts Interviewed
212 Consumers Consulted
Zero products received from manufacturers.

We purchase every product we review with our own funds — we never accept anything from product manufacturers.

Just like their human owners, pets can also suffer from a variety of problems associated with the urinary tract and kidneys. Infections, incontinence, and kidney stones are the most common ailments, but some pets are also prone to more serious conditions of the renal system, including blockage, renal failure, and diseases that result in the need for a diuretic. The good news is that there are many medications that effectively treat pet urinary tract and kidney health conditions. If your pet is experiencing concerning symptoms, have him evaluated by your veterinarian. If the diagnosis is related to the renal system, prescription medications or supplements may be recommended that you can purchase hassle-free online.

Other Products We Considered
The BestReviews editorial team researches hundreds of products based on consumer reviews, brand quality, and value. We then choose a shorter list for in-depth research and testing before finalizing our top picks. These are the products we considered that ultimately didn't make our top 5.
Coco and Luna
Urinary Tract Support
Sunergetic
Premium Kidney Cleanse Supplement
Chew + Heal Labs
Soft Chews - Supports Healthy Urinary Tract
BestLife4Pets
Natural Urinary Tract Infection Treatment
UroMAXX
Urinary Tract, Kidney & Bladder
BestLife4Pets
UTI Urinary Tract & Kidney Support Treatment
Zesty Paws
Cranberry for Dogs
PetHonesty
Cranberry for Dogs
Sunergetic
Premium Uric Acid Support Supplement
HomeoPet
UTI Plus Urinary Tract Infection
Pet Wellbeing
Urinary Gold for Dogs
Mighty Petz
UTI Urinary Tract Infections & Kidney Health
Alfa Pet
Kidney Bladder Urinary Support
Purina Pro Plan
Focus Urinary Tract Health
Dr. Oscar
NEW Organic Dog UTI Treatment
GNC
Pets Ultra Mega Urinary Support
maxxipaws
maxxiUtract Urinary and Bladder Supplement
Solid Gold
Berry Balance Supplement Urinary Tract Health
Dr. Mercola
Optimal Urinary Tract Health and Function
Amate Life
Cranberry for Dogs Urinary Tract
Nutri-Vet
Reduce Urinary Incontinence & Facilitate Bladder
Emerald Pet
Feline Health and Urinary Tract Control
Pet Health Pharma
Urinary Tract Infection Support
Get Naked
Urinary Health Crunchy Treats
Pet Naturals
Urinary Tract Supplement
K9 Nature Supplements
Bladder and Urinary Support for Dogs
See more

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Our Top Picks
Baytril (Enrofloxacin) Tablets for Dogs & Cats
Best of the Best
Baytril (Enrofloxacin)
Tablets for Dogs & Cats
Shop Now
NOW Pets Urinary Support Dog & Cat Supplement, 90 count
Best Bang for the Buck
NOW Pets
Urinary Support Dog & Cat Supplement, 90 count
Shop Now
Proin Chewable Tablets for Dogs
Proin
Chewable Tablets for Dogs
Shop Now
Salix (Furosemide) Tablets for Dogs and Cats
Salix (Furosemide)
Tablets for Dogs and Cats
Shop Now
Normosol-R Electrolyte Injection Solution
Normosol-R
Electrolyte Injection Solution
Shop Now