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Best Pet Urinary Tract & Kidney Medicine

Updated March 2024
Bottom line
Pros
Cons
Best of the Best
Baytril (Enrofloxacin) Tablets for Dogs & Cats
Baytril (Enrofloxacin)
Tablets for Dogs & Cats
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Best for Infections
Bottom Line

A highly-effective antibiotic that works well for treating urinary tract infections when taken as prescribed. Be sure your pet drinks plenty of water when taking this medication.

Pros

An effective antibiotic that is commonly prescribed to treat urinary tract infections. Used for dogs and cats. Many pets experience quick relief once they begin taking this medication.

Cons

Side effects such as stomach upset, lethargy, and elevated liver enzymes are possible. Dairy foods must be withheld for 2 hours after dosing for best results.

Best Bang for the Buck
Beloved Pets Cat & Dog Urinary Tract Infection Medicine
Beloved Pets
Cat & Dog Urinary Tract Infection Medicine
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For Urinary Tract Health
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This wide-ranging medicine helps with kidney stones, UTIs, general irritation, and bladder support.

Pros

It’s cranberry flavored and a liquid, making it easy to hide in food or mixed with broth and water. There are detailed dosage instructions and it contains no chemicals, preservatives or fillers.

Cons

Some had issues with the included dropper not pulling in enough medicine.

Proin Chewable Tablets for Dogs
Proin
Chewable Tablets for Dogs
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For Canine Incontinence
Bottom Line

Ask your veterinarian about Proin if your best friend tends to leak urine, as it is a medication that is quite effective at controlling this troublesome renal system concern.

Pros

Earns praise from dog owners for how well it controls continence. Effective for most dogs, and is frequently prescribed to senior canines that are prone to urinary leaking issues. Prevents leaks by tightening muscles in the urethra and bladder.

Cons

Not for cats. Although chewable, some dogs don't like the flavor, so owners still may have to conceal the tablets in treats or food.

Salix (Furosemide) Tablets for Dogs and Cats
Salix (Furosemide)
Tablets for Dogs and Cats
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Effective Diuretic
Bottom Line

In spite of possible side effects, this medication outweighs the risks when prescribed for pets with serious ailments such as renal or heart failure.

Pros

This diuretic is a trusted medication that is frequently prescribed to promote the removal of fluid due to a variety of health conditions, including kidney failure. Can be prescribed for dogs and cats. Pills are scored and easy to split.

Cons

Possibility of side effects, some potentially serious, such as dehydration, electrolyte imbalance, vomiting, and depressed mood. Some pets may spit them out.

Merck Incurin Tablets
Merck
Incurin Tablets
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For Post-op Issues
Bottom Line

These tablets target issues related to dogs that have been spayed, reducing or eliminating post-surgery urinary incontinence.

Pros

Dosage is only once daily and the amount does not change based on age or weight. Full treatment lasts for a minimum of 2 weeks. The tablets are easy to hide in a treat or be crushed and mixed with food or water and broth.

Cons

It’s for dog use only and requires a prescription, so you need your vet's authorization.

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BestReviews spends thousands of hours researching, analyzing, and testing products to recommend the best picks for most consumers. We only make money if you purchase a product through our links, and all opinions about the products are our own. About BestReviews  
BestReviews spends thousands of hours researching, analyzing, and testing products to recommend the best picks for most consumers. We buy all products with our own funds, and we never accept free products from manufacturers.About BestReviews 
HOW WE TESTED

We recommend these products based on an intensive research process that's designed to cut through the noise and find the top products in this space. Guided by experts, we spend hours looking into the factors that matter, to bring you these selections.

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Just like their human owners, pets can also suffer from a variety of problems associated with the urinary tract and kidneys. Infections, incontinence, and kidney stones are the most common ailments, but some pets are also prone to more serious conditions of the renal system, including blockage, renal failure, and diseases that result in the need for a diuretic. The good news is that there are many medications that effectively treat pet urinary tract and kidney health conditions. If your pet is experiencing concerning symptoms, have him evaluated by your veterinarian. If the diagnosis is related to the renal system, prescription medications or supplements may be recommended that you can purchase hassle-free online.