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Best Pet Seizure & Epilepsy Medications

Updated March 2024
Bottom line
Pros
Cons
Best of the Best
K-BroVet 500 Chewable Tablets
K-BroVet
500 Chewable Tablets
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Liver Flavored
Bottom Line

Featuring 60 delicious treat-like chicken liver chews per bottle, K-BroVet delivers a potent anti-seizure medication that your dog will be thrilled to wolf down, making “medicine time” as engaging as “treat time.”

Pros

Available in 2 dosage sizes, 250 mg and 500 mg. Tasty liver flavored chewable tablet. Treats seizure-related disorders. Can be used alongside other anti-seizure medications.

Cons

Intended for dogs only. Side effects may include increased hunger, increased thirst, and nausea.

Best Bang for the Buck
Levetiracetam Levetiracetam (Generic) Tablets
Levetiracetam
Levetiracetam (Generic) Tablets
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Bargain Pick
Bottom Line

Affordably priced and featuring few major side effects, Levetiracetam is easily the cheapest way to curb your dog or cat’s seizures.

Pros

Extremely affordable per-tablet price. Available in 4 dosages: 250 mg, 500 mg, 750 mg, and 1,000 mg. Tablet is easy to split. Controls seizures caused by epilepsy. Prescribed for dogs, cats, and even humans.

Cons

This seizure medication may cause drowsiness. Not recommended for pregnant animals.

Primidone Primidone (Generic) Tablets
Primidone
Primidone (Generic) Tablets
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Long-term Treatment
Bottom Line

Primidone is a moderately-priced prescription epilepsy medication made for greatly reducing seizures, and can be used for long periods as needed for treating chronic conditions.

Pros

Greatly reduces severity and frequency of seizures and convulsions caused by epilepsy. Tablet form is easy to hide in pill pocket-style treats. Designed for long-term epilepsy treatment.

Cons

Intended for dogs only. Side effects may include liver toxicity, weight gain, and increased thirst.

Zonisamide Zonisamide (Generic) Capsules
Zonisamide
Zonisamide (Generic) Capsules
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For Dogs & Cats
Bottom Line

Although capsules aren’t as easy to feed to your cat or dog as a tablet, it is worth asking your vet to implement Zonisamide as an additional treatment to help control their seizures.

Pros

Affordable. Available in 3 dosage sizes, 25 mg, 50 mg, and 100 mg. Helps prevent seizures. Can be used with other anti-seizure medications. Prescribed to dogs and cats.

Cons

Side effects may include drowsiness, loss of appetite, and lack of coordination.

K-BroVet K-BroVet Oral Solution
K-BroVet
K-BroVet Oral Solution
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Butterscotch Flavored
Bottom Line

Easy to measure out for your dog’s size, and easier to administer because of its yummy butterscotch and vanilla taste, this oral solution is a solid medication for curbing your dog’s seizures.

Pros

Available in 2 oz. and 10 oz. bottles. Dogs love its butterscotch-vanilla flavor. Treats seizure-related disorders. Can be used with additional anti-seizure treatments. For all dog sizes and breeds.

Cons

Side effects may include lethargy, constipation, and drowsiness.

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BestReviews spends thousands of hours researching, analyzing, and testing products to recommend the best picks for most consumers. We only make money if you purchase a product through our links, and all opinions about the products are our own. About BestReviews  
BestReviews spends thousands of hours researching, analyzing, and testing products to recommend the best picks for most consumers. We buy all products with our own funds, and we never accept free products from manufacturers.About BestReviews 
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Epilepsy is only one of many potential causes for the seizures, convulsions, and shaking that may effect your dog or cat, and while it may not be easy to pinpoint the exact cause in every case, there are multiple medications to help curb or eliminate your pet’s seizures. Seizure and epilepsy medications for pets are  offered in tablet, capsule, and liquid formulas, and we suggest asking your vet for an option that your pet will easily consume. Since there are a number of pet seizure and epilepsy medications available, it is well worth researching these, especially effective options to begin treating your best friend as soon as possible.